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Multiples Myelom / Multiple Myeloma

27.10.2010

http://medicalcenter.osu.edu/mediaroom/Pages/release.aspx?newsID=6089
Study Identifies Key Molecules In Multiple Myeloma
Multiples-Myelom miR-192, miR-194 and miR-215

15.11.2011

http://medicalxpress.com/news/2011-11-scientists-defeat-hurdle-eradicating-inactive.html
Scientists defeat hurdle to eradicating inactive multiple myeloma cells
multiple-myeloma, Chk1 inhibitor AZD7762, MEK1/2 inhibitor AZD6244

22.8.2007

http://idw-online.de/pages/de/news221591
Europapremiere in Heidelberg: Neues Medikament bei Knochenmarkkrebs
Wirkstoff Lenalidomid, multiples Myelom Europapremiere Heidelberg

20.1.2006

http://idw-online.de/pages/de/news143282
Multiples Myelom: Tumorzellen forcieren Abbau der Knochen
Myelom

26.12.2006

http://idw-online.de/pages/de/news181448
Ziel: Krebsgene abschalten
Krebs Gen, Multiples Myelom, Ras und YB-1

25.7.2012

http://www.eurekalert.org/pub_releases/2012-07/jtcc-jtc072412.php
John Theurer Cancer Center researchers shed light on new multiple myeloma therapy
multiple-myeloma-therapy

13.12.2009

http://www.eurekalert.org/pub_releases/2009-12/uotm-dsp_1120509.php
Drug shows positive responses, low side-effects in multiple myeloma
proteasome inhibitor carfilzomib bortezomib

7.6.2007

http://www.eurekalert.org/pub_releases/2007-06/i-id-nmm060407.php
New multiple myeloma treatment induced total remission in 33 percent of patients
M-protein

28.12.2006

http://www.eurekalert.org/pub_releases/2006-11/asoh-kca110306.php
Keeping cancer at bay: Long-term therapy in the fight against multiple myeloma
bay pamidronate

23.11.2012

http://cancerres.aacrjournals.org/content/72/20/5348.short?rss=1
Sorafenib Has Potent Antitumor Activity against Multiple Myeloma In Vitro, Ex Vivo, and In Vivo in the 5T33MM Mouse Model
B-cell-malignancy CD138+ Mcl-1 ABT737 Bcl-2/Bcl-xL

6.1.2011

http://www.physorg.com/news/2011-01-potential-multiple-myeloma-therapy.html
Potential new multiple myeloma therapy developed
IRF4 multiple-myeloma-therapy

1.10.2010

http://www.eurekalert.org/pub_releases/2010-09/ttgr-tcs092910.php
TGen-Mayo Clinic study discovers role of DNA methylation in multiple myeloma blood cancer
DNA-methylation, multiple-myeloma-blood-cancer, hypomethylation hypermethylation

5.7.2008

http://www.nih.gov/news/health/jun2008/nci-22.htm
Blocking a Single Protein Proves Toxic to Myeloma Cells in Laboratory Studies
IRF4 multiple myeloma

10.12.2012

http://www.eurekalert.org/pub_releases/2012-12/tmsh-nmm120912.php
New multiple myeloma drug shows promise in treating people with advanced disease
oral-agent dexamethasone pomalidomide

15.8.2012

http://www.eurekalert.org/pub_releases/2012-08/vcu-sdn081412.php
Scientists devise new strategy to destroy multiple myeloma
cyclin-dependant kinase (CDK)

21.6.2012

http://www.eurekalert.org/pub_releases/2012-06/nyph-sas062112.php
Stopping and starting cancer cell cycle weakens and defeats multiple myeloma

4.6.2012

http://www.hematology.org/News/2012/8422.aspx
Carfilzomib Demonstrates Efficacy As New Frontline Treatment Regimen for Multiple Myeloma

16.5.2012

http://www.eurekalert.org/pub_releases/2012-05/ohs-lpd051512.php
Lenalidomide prolongs disease control for multiple myeloma patients after stem cell transplant
stem-cell-transplant

11.5.2012

http://www.eurekalert.org/pub_releases/2012-05/ulcc-ss051112.php
Study shows benefit of new maintenance therapy for multiple myeloma

2.5.2012

http://www.eurekalert.org/pub_releases/2012-05/arrs-ldw041912.php
Low-dose whole-body CT finds disease missed on standard imaging for patients with multiple myeloma

10.9.2011

http://www.insidemoffitt.com/content.cfm?page_id=392&press_release_id=423
Moffitt Cancer Center Researchers Use New Tool To Counter Multiple Myeloma Drug Resistance

10.1.2012

http://medicalxpress.com/news/2012-01-effective-treatment-multiple-myeloma.html
Towards more effective treatment for multiple myeloma
Hsp70 MAL3-101

9.1.2012

http://www.eurekalert.org/pub_releases/2012-01/sdmc-tme010912.php
Towards more effective treatment for multiple myeloma
Hsp70 MAL3-101

28.9.2006

http://www.basqueresearch.com/berria_irakurri.asp?Gelaxka=1_1&hizk=I&Berri_Kod=1029
An advanced genetic diagnostic method for multiple myeloma

15.8.2008

http://www.biomedcentral.com/1755-8794/1/37
An integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma

7.10.2008

http://www.casesjournal.com/content/1/1/207
IgM multiple myeloma presenting with spinal cord compression caused by plasmacytoma: a case report
plasmacytoma

13.12.2011

http://medicalxpress.com/news/2011-12-peptide-cocktail-elicits-immune-response.html
Peptide 'cocktail' elicits immune response to multiple myeloma
antigenic peptides, Immunotherapy

12.12.2011

http://www.eurekalert.org/pub_releases/2011-12/mc-mch120911.php
Mayo Clinic: How patients will respond to immunomodulator therapy for multiple myeloma
cereblon

11.12.2011

http://medicalxpress.com/news/2011-12-patients-immunomodulator-therapy-multiple-myeloma.html
How patients will respond to immunomodulator therapy for multiple myeloma
cereblon

23.3.2011

http://www.eurekalert.org/pub_releases/2011-03/biom-fla032111.php
First look at the full multiple myeloma genome reveals new insights, discoveries

23.3.2011

http://www.eurekalert.org/pub_releases/2011-03/jtcc-rsm032111.php
Researchers sequence multiple myeloma genome in landmark Nature study
methylation, NF-Kappa Beta signaling

23.3.2011

http://www.physorg.com/news/2011-03-sequence-multiple-myeloma-genome-landmark.html
Researchers sequence multiple myeloma genome in landmark study
methylation, NF-Kappa Beta signaling

11.2.2011

http://www.physorg.com/news/2011-02-combine-agents-multiple-myeloma-cells.html
Research first to combine targeted agents to kill multiple myeloma cells
Chk1 inhibitors, ERK1/2

11.2.2011

http://www.eurekalert.org/pub_releases/2011-02/vcu-vm021011.php
VCU Massey first to combine targeted agents to kill multiple myeloma cells
Chk1 inhibitors, ERK1/2

9.12.2010

http://www2.med.umich.edu/prmc/media/newsroom/details.cfm?ID=1852
Drug combination shows promise for newly diagnosed blood cancer patients
multiple myeloma, carfilzomib

14.10.2010

http://www.eurekalert.org/pub_releases/2010-10/uoc--usd101410.php
UCSB scientists discover inner workings of potent cancer drug
maytansine, multiple myeloma and B-cell lymphoma

1.10.2010

http://www.physorg.com/news205057984.html
Study discovers role of DNA methylation in multiple myeloma blood cancer

16.7.2010

http://www.eurekalert.org/pub_releases/2010-07/uu-ndb071610.php
New discovery brings hope to treatment of incurable blood cancer
Multiple myeloma, Polycomb repressor complex

23.1.2009

http://www.eurekalert.org/pub_releases/2008-12/wsw-asr121008.php
Analysis shows revlimid plus dexamethasone increases overall survival in multiple myeloma patients

19.9.2007

http://www.newswise.com/articles/view/533274
Gene Profiling Can Single Out the Worst Cases of Multiple Myeloma and Guide Therapy

8.6.2008

http://www.biomedcentral.com/1471-2172/9/22
Humoral immunoreactivity to gliadin and to tissue transglutaminase is present in some patients with multiple myeloma

1.5.2008

http://www.cancerci.com/content/8/1/4
Ku86 exists as both a full-length and a protease-sensitive natural variant in multiple myeloma cells

1.5.2008

http://www.jibtherapies.com/content/6/1/2
Use of ultraviolet light irradiated multiple myeloma cells as immunogens to generate tumor-specific cytolytic T lymphocytes
cytolytic immunogens

7.4.2008

http://www.translational-medicine.com/content/6/1/15
The pituitary tumor transforming gene 1 (PTTG-1): an immunological target for multiple myeloma

21.12.2007

http://www.sciencedaily.com/releases/2007/12/071211232835.htm
Three-drug Combination 'Extremely Promising' As First-line Therapy For Multiple Myeloma

13.12.2007

http://www.eurekalert.org/pub_releases/2007-12/dci-tc121107.php
3-drug combination 'extremely promising' as first-line therapy for multiple myeloma

29.11.2007

http://www.newswise.com/articles/view/535613/?sc=rsla
Researchers Transfer Immune Response to Myeloma Patient, Study Points to Potential Cancer Vaccination
UNIVERSITY ARKANSAS MEDICAL SCIENCES, MULTIPLE MYELOMA, STEM CELL, BONE MARROW, STEM CELL TRANSPLANT, MAGE-A3 PROTEIN multiple myeloma

29.11.2007

http://www.cbc.ca/health/story/2007/11/22/thalidomide-study.html?ref=rss
Thalidomide resurfaces as treatment for multiple myeloma

29.11.2007

http://www.sciencedaily.com/releases/2007/11/071121172243.htm
Drug Combination Effective For Multiple Myeloma
dexamethasone

28.10.2007

http://www.eurekalert.org/pub_releases/2007-04/mc-mcc041207.php
Mayo Clinic Cancer Center researcher finds mold by-product kills multiple myeloma

19.9.2007

http://www.eurekalert.org/pub_releases/2007-09/aafc-gpc091107.php
Gene profiling can single out the worst cases of multiple myeloma and guide therapy

14.3.2007

http://www.eurekalert.org/pub_releases/2007-03/mc-mcc030507.php
Investigating the measles virus as a tool to kill multiple myeloma
Angela Dispenzieri

14.12.2006

http://www.eurekalert.org/pub_releases/2006-12/mc-mcc120706.php
Mayo Clinic Cancer Center -- individualizing treatment for multiple myeloma patients

4.6.2012

http://www.eurekalert.org/pub_releases/2012-06/uocm-dch060312.php
Drug combination highly effective for newly diagnosed myeloma patients
multiple-myeloma proteasome-inhibitor carfilzomib

13.2.2012

http://medicalxpress.com/news/2012-02-powerful-myeloma-treatment-regimen-al.html
Powerful myeloma treatment regimen shows promise for AL amyloidosis
multiple-myeloma AL-amyloidosis

13.2.2012

http://www.hematology.org/News/2012/7748.aspx
Powerful Myeloma Treatment Regimen Shows Promise for AL Amyloidosis
multiple-myeloma

22.12.2011

http://idw-online.de/pages/de/news457491
Genetische Risikofaktoren für Entstehung eines seltenen Knochenmarkkrebses entdeckt
Multiples-Myelom, genomweite Assoziationsstudie (GWAS)

12.12.2012

http://www.newscientist.com/article/dn22613-soupedup-immune-cells-force-leukaemia-into-remission.html
Souped-up immune cells force leukaemia into remission
multiple-myeloma genetically-engineered-T-cells, NY-ESO-1 and LAGE-1, Gentechnik-gegen-Multiples-Myelom

3.6.2010

http://www.eurekalert.org/pub_releases/2010-06/wuso-bds060210.php
Bone drug suppresses wandering tumor cells in breast cancer patients
zoledronic acid (Zometa) metastatic breast cancer multiple-myeloma bone-metastases

9.6.2010

http://www.eurekalert.org/pub_releases/2010-06/uomh-nmd060710.php
New myeloma drug shows promise in early testing
CS1 elotuzumab bortezomib myeloma-drug, multiple myeloma

15.12.2006

http://www.eurekalert.org/pub_releases/2006-12/dci-dcp120806.php
Drug combination proves effective against myeloma in Phase I trial
bortezomib (Velcade) lenalidomide (Revlimid), multiple myeloma

26.9.2007

http://www.sciencedaily.com/releases/2007/09/070910132856.htm
Human C-reactive Protein Regulates Myeloma Tumor Cell Growth And Survival
CRP IL-6 multiple-myeloma

16.9.2007

http://www.eurekalert.org/pub_releases/2007-09/cp-hcp090407.php
Human C-reactive protein regulates myeloma tumor cell growth and survival
IL-6 PI3K/Akt, ERK, and NF-kB multiple-myeloma

10.9.2012

http://www.eurekalert.org/pub_releases/2012-09/dci-mse090712.php
Molecule shows effectiveness against drug-resistant myeloma
P5091 USP7 HDM2 Multiple-Myeloma

12.12.2011

http://www.hematology.org/News/2011/7364.aspx
Emerging Lymphoma and Myeloma Treatments Focus on Improving Individual Patient Response
Cereblon Lenalidomide Pomalidomide multiple-myeloma

8.12.2011

http://medicalxpress.com/news/2011-12-drug-combination-highly-effective-newly.html
Drug combination highly effective for newly diagnosed myeloma patients, study finds
Carfilzomib multiple-myeloma

13.10.2010

http://www.physorg.com/news/2010-10-high-response-phase-iii-trial-chemotherapy.html
High response rates seen in phase-III trial of chemotherapy, new drug and stem cells in myeloma
lenalidomide multiple-myeloma

14.6.2008

http://www.jhoonline.org/content/1/1/6
Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways
Histone deacetylase (HDAC) inhibitors multiple-myeloma

9.12.2007

http://www.eurekalert.org/pub_releases/2007-12/sjcr-sjf120607.php
St. Jude finds mechanism for faulty protein disposal
myeloma B-lymphocytes Proteasome-inhibitors retrotranslocons PROTEASOME, endoplasmic-reticulum, multiple-myeloma

25.12.2007

http://www.eurekalert.org/pub_releases/2007-04/uotm-ndp041907.php
Novel drug preventing protein recycling shows potential for treating leukemia
proteasome inhibitor, NPI-0052, bortezomib, histone deacetylase (HDAC) inhibitor, multiple-myeloma

14.7.2010

http://www.eurekalert.org/pub_releases/2010-07/jtcc-sme071210.php
Study makes exciting progress in elucidating the mechanisms of bortezomib in lymphoma
multiple-myeloma