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Krebs und mTOR / Cancer and mTOR


2.11.2010

http://www.physorg.com/news/2010-11-drug-decreases-alcohol-cravings.html
Drug decreases alcohol cravings
Rapamycin mTORC1
13.9.2010

http://www.eurekalert.org/pub_releases/2010-09/chb-ant091010.php
A new target in polycystic kidney disease
mTOR PKD1
10.2.2010

http://news.wustl.edu/news/Pages/20233.aspx
Researchers discover new way to kill pediatric brain tumors
STAT3 mTOR NF1
10.8.2008

http://www.newswise.com/articles/view/543212/
How Tumor Suppress or Inhibits Cell Growth
p53, Sestrin1 Sestrin2 mTOR
1.5.2008

http://www.sciencedaily.com/releases/2008/04/080424121443.htm
Ancient Signaling Pathway Tells Cells To Conserve Energy When Food Is Scarce
AMPK mTOR LKB1 raptor
12.1.2008

http://www.eurekalert.org/pub_releases/2008-01/cchm-tds010708.php
Transplant drug sirolimus shrinks tumors, improves lung function
mTOR
31.1.2008

http://www.antikoerper-online.de/news/3/219/Rheb+aktiviert+mTOR+indem+es+FKBP38+entgegenwirkt.htm
Rheb aktiviert mTOR, indem es FKBP38 entgegenwirkt

12.1.2008

http://www.brightsurf.com/news/headlines/35230/Genetic_breakthrough_offers_promise_in_tackling_kidney_tumors.html
Genetic breakthrough offers promise in tackling kidney tumors
TSC1 TSC2 mTOR
25.2.2009

http://www.sciencecentric.com/news/09021129-drug-discovery-short-circuits-cancer-growth.html
Drug discovery short-circuits cancer growth
rapamycin mTOR
27.2.2009

http://www.wienerzeitung.at/DesktopDefault.aspx?TabID=4103&Alias=wzo&cob=399161
Wiener Forschern gelang Durchbruch
dumme-Überschrift, Funktion des Proteins mTOR geklärt, Rapamycin Temsirolimus Everolimus, Marcus Säemann, Thomas Weichhart
3.3.2008

http://www.plosone.org:/article/info%3Adoi%2F10.1371%2Fjournal.pone.0001598
Hsf1 Activation Inhibits Rapamycin Resistance and TOR Signaling in Yeast Revealed by Combined Proteomic and Genetic Analysis

18.2.2008

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0001598
Hsf1 Activation Inhibits Rapamycin Resistance and TOR Signaling in Yeast Revealed by Combined Proteomic and Genetic Analysis

14.11.2007

http://www.biomedcentral.com/1471-2407/7/208
Coupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma Cells

2.10.2010

http://interactive.snm.org/index.cfm?PageID=10104
Evaluation of Targeted Therapy in Ovarian Cancer
mTOR cisplatin-resistance Everolimus
20.7.2010

http://www.eurekalert.org/pub_releases/2010-07/joci-iao071410.php
Impaired activity of the protein MTOR a strain on the heart

9.8.2010

http://www.eurekalert.org/pub_releases/2010-08/uoc--ibn080510.php
In breakthrough, nerve connections are regenerated after spinal cord injury
PTEN mTOR
17.3.2010

http://news.ucsf.edu/releases/blocking-cancer-in-its-path-new-cellular-defect-discovered/
Blocking cancer in its path: New cellular defect discovered
mTOR
12.7.2009

http://www.antikoerper-online.de/news/3/464/FBXW7+markiert+mTOR+zum+Abbau+und+kooperiert+mit+PTEN+bei+der+Tumorsuppression/
FBXW7 markiert mTOR zum Abbau und kooperiert mit PTEN bei der Tumorsuppression
PTEN ENZYM 3 UBIQUITIN
7.10.2008

http://www.jci.org/articles/view/34764
Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model
AKT mTOR
7.10.2008

http://www.jci.org/articles/view/33337
Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells
mTOR
24.5.2008

http://www.scienceblog.com/cms/drug-fends-kidney-cancer-progression-16448.html
Drug fends off kidney cancer progression
everolimus mTOR
24.11.2007

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0001217
PRAS40 and PRR5-Like Protein Are New mTOR Interactors that Regulate Apoptosis
PRR5-Like-Protein
9.11.2007

http://www.sciencemag.org/cgi/content/full/318/5852/977?rss=1
[REPORTS] Rheb Activates mTOR by Antagonizing Its Endogenous Inhibitor, FKBP38

25.5.2006

http://www.eurekalert.org/pub_releases/2006-05/uotm-tvc050206.php
Targeted virus compels cancer cells to eat themselves
hTERT-Ad Autophagie Gliom mTOR
26.2.2005

http://www.eurekalert.org/pub_releases/2005-02/wifb-rit021705.php
Researchers identify target for cancer drugs
Ziel Krebs Medikament, Prostata Gehirn, Tumor-Suppressor-Protein PTEN, Lipid, Zellmembran, David Sabatini, mTOR, Rictor, Phosphorylation
18.2.2010

http://www.eurekalert.org/pub_releases/2010-02/uotm-rds021710.php
Researchers discover second protective role for tumor-suppressor
TSC2 LKB1 TORC1 ROS AMPK
11.1.2010

http://www.eurekalert.org/pub_releases/2010-01/chb-rat010810.php
Research adds to evidence that autism is a brain 'connectivity' disorder
tuberous sclerosis complex (TSC), TSC2 mTOR
30.12.2009

http://www.eurekalert.org/pub_releases/2009-12/joci-ua122209.php
Notch'ing up a role in the multisystem disease tuberous sclerosis complex
TSC1 TSC2
7.10.2008

http://content.nejm.org/cgi/content/short/359/13/1367?rss=1&query=current
REVIEW ARTICLE: Molecular Origins of Cancer: Lung Cancer
EGFR, KRAS, the PI3K-Akt-mTOR complex, and TITF1
16.9.2007

http://science.orf.at/science/news/148481
Molekulare Ursachen für Tuberöse Sklerose geklärt
TSC1 TSC2
28.8.2006

http://science.orf.at/science/news/145044
Genetische Ursachen der Tuberösen Sklerose
Genetisch Ursache Tuberöse Sklerose, TSC1 TSC-2 Gen Hamartin TSC1 Tuberin TSC-2 BAD-Gen
4.10.2009

http://www.physorg.com/news169152201.html
Grapefruit juice found to give cancer treatment a boost
LIVER rapamycin
25.2.2010

http://www.eurekalert.org/pub_releases/2010-02/uoth-rrl022410.php
Rapamycin rescues learning, memory in Alzheimer's mouse model

27.8.2006

http://www.innovations-report.de/html/berichte/biowissenschaften_chemie/bericht-69138.html
Rapamycin shown to inhibit angiogenesis
VEGF
9.8.2006

http://www.eurekalert.org/pub_releases/2006-08/bi-ipc080206.php
Insulin pathway component explains insulin resistance, age-associated metabolic syndrome
TOR Gen, target of rapamycin
19.11.2008

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0003558
Anti-EGFR Antibody Efficiently and Specifically Inhibits Human TSC2-/- Smooth Muscle Cell Proliferation. Possible Treatment Options for TSC and
Proliferation TSC1 TSC2
10.7.2009

http://www.newscientist.com/article/dn17439-new-clues-in-search-for-elixir-of-youth.html
New clues in search for elixir of youth
Rapamycin
9.7.2009

http://www.wissenschaft.de/wissenschaft/news/305117.html
Wirkstoff lässt Mäuse zehn Prozent länger leben
Rapamycin
8.10.2007

http://www.news-medical.net/?id=30621
Rapamycin and Gleevec reverses effects of portal hypertension in rats

6.6.2007

http://www.eurekalert.org/pub_releases/2007-06/asu-tbt060107.php
The bee that would be queen
Kaste, RNAi, TOR (target of rapamycin)
12.4.2007

http://www.eurekalert.org/pub_releases/2007-04/uomh-spi041107.php
Study pries into ovarian cancer's deadly secrets
Rapamycin
28.9.2006

http://www.eurekalert.org/pub_releases/2006-09/si-dff090706.php
Distinguishing friend from foe in the battle against cancer
oncoproteins rapamycin, chronic myelogenous leukemia, NF-kB
26.8.2006

http://www.eurekalert.org/pub_releases/2006-08/bidm-rst081106.php
Rapamycin shown to inhibit angiogenesis
Akt pathway
8.6.2008

http://www.news-medical.net/?id=38801
Anti-rejection drug sirolimus may prolong organ life in noncompliant kidney transplant patients

25.12.2010

http://www.redorbit.com/news/science/1970750/mammalian_aging_process_linked_to_overactive_cellular_pathway/index.html
Mammalian Aging Process Linked To Overactive Cellular Pathway
mTORC1
7.10.2008

http://www.jci.org/articles/view/34739
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer